Handbook of Applied Colloid & Surface Chemistry (2 Volume by Krister Holmberg

By Krister Holmberg

The 'Handbook of utilized floor and Colloid Chemistry' is a different reference paintings that addresses crucial functions, phenomena and analytical suggestions of rainy floor chemistry. together with an important wealth of customarily essentially oriented info it really is written via a world group of popular scientists and grants with authority and event content material that completely covers the entire significant applications.

Helpfully organised into 5 components the 2 volumes contain a double column layout and various diagrams. The ordinary constitution permits readers to speedily find issues of specific curiosity and the in actual fact outlined sections current the subject in a radical and complete manner.

half One: floor Chemistry in Important
Technologies
Covers commercial and family makes use of - from life
science-related purposes all through to business processes.

half : Surfactants
completely addresses the main houses and
purposes of crucial surfactants - the
major device in floor and colloid chemistry.

half 3: Colloidal platforms and Layer
constructions at Surfaces
offers complete details on 4 vital colloidal
platforms such as:
-- stable dispersions (suspensions)
-- Foams
-- Vesicles and liposomes
-- Microemulsions

half 4: Phenomena in floor Chemistry
greatly reports the real phenomena of
foam breaking, solubilization, rheological results of
surfactants, in addition to wetting, spreading and
penetration.

half 5: research and Characterization in
floor Chemistry
to aid the researcher focussing on a particular
challenge the part is organised through surface
parameter instead of by means of technique or process.

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Additional resources for Handbook of Applied Colloid & Surface Chemistry (2 Volume Set)

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36)) limitations to their general application in drug delivery. However, this high surfactant concentration can also contribute to the functional advantages of such systems, which is most probably the case for topical administration of both hydrophobic and hydrophilic substances using microemulsions. g. 12) (166). g. when used for treating a number of skin disorders, than the corresponding water, propylene glycol and Carbopol "gel", through full-thickness abdominal skin (168). The origin of the advantageous effects of microemulsions for topical drug delivery is not entirely understood.

The system used for this consisted of monoolein, sesame oil and metronidazole. By administering such a system as a suspension, which transforms into either a cubic or a reversed hexagonal phase at higher water content, it is possible to use the excess water present in the oral cavity in order to achieve the transition from the relatively low viscous, and hence easily administered, L2 formulation, into the stiffer cubic and reversed hexagonal phases in situ (cf. 13). In particular, the reversed hexagonal phase was found to have the most favourable sustained release properties.

For example, sodium salicylate has been found to significantly alter the stability region of microemulsions prepared from lecithin, and specifically to increase the extension of the microemulsion region (22). Furthermore, Carlfors et al. studied microemulsions formed by water, isopropyl myristate and nonionic surfactant mixtures, as well as their solubilization of lidocaine, and found that the surface active but lipophilic lidocaine lowered the phase inversion temperature (PIT) (23). This is what would be expected from simple packing considerations, since increasing the effective oil volume favours a decrease in the curvature towards the oil, as well as the formation of reversed structures.

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