Nutrition & Immunity by M. Eric Gershwin, Richard S. Beach, Lucille S. Hurley

By M. Eric Gershwin, Richard S. Beach, Lucille S. Hurley

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Immunofluorescence techniques are used to identify immunoglobulin receptors on B cells, and rosetting techniques are used to identify T and B cells. Whenever possible, the clinician should use more than one in vitro test of lymphocyte function, since each assay may measure a distinct subpopulation of cells. Furthermore, present evidence indicates that lymphocytes are compartmentalized; that is, cells in the blood may be functionally different from those in lymph nodes or spleen. Therefore, sampling blood lymphocytes alone may not yield representative results.

R. Stiehm and G. S. Rachelefsky. Control of antibody synthesis. In "Allergy: Principles and Practice" (E. , C. E. Reed, and E. F. ), p. 000. Mosby, St. Louis, Missouri, 1978. 38 2. Evaluation of Immunological Function and quantitation of major immunoglobulin classes. Serum electrophoresis provides an overview of the five major electrophoretic groups of serum proteins (Fig. 2). Zone electrophoresis also provides ready qualitative assessment of serum or urine abnormalities. This is particularly valuable for the detection of myeloma proteins and Waidenstrom macroglobulins (and Bence Jones proteins) as discrete bands discernible in addition to the usual serum or urine protein peaks.

Stiehm and G. S. Rachelefsky. Control of antibody synthesis. In "Allergy: Principles and Practice" (E. , C. E. Reed, and E. F. ), p. 000. Mosby, St. Louis, Missouri, 1978. 38 2. Evaluation of Immunological Function and quantitation of major immunoglobulin classes. Serum electrophoresis provides an overview of the five major electrophoretic groups of serum proteins (Fig. 2). Zone electrophoresis also provides ready qualitative assessment of serum or urine abnormalities. This is particularly valuable for the detection of myeloma proteins and Waidenstrom macroglobulins (and Bence Jones proteins) as discrete bands discernible in addition to the usual serum or urine protein peaks.

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