Principles of Animal Biology 2nd Edition by Lancelot Hogben

By Lancelot Hogben

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Bacterial β-glucosidase activity was increased in TOS-fed rats. Significant decrease in β-glucuronidase and ammonia. Rowland et al. Probiotic plus prebiotic was more effective. 1 units in all subjects. 3 A 14% decrease in mean β-glucuronidase activity after 2 weeks. Lidbeck et al. 05). Spanhaak et al. (1998) No change in faecal β-galactosidase and b-glucuronidase. Significant increase in β-glucosidase activity. Marteau et al. (1990b) A decrease in β-glucuronidase and β-glucosidase activity. Ayebo et al.

1997) who have provided evidence of immune system modulation in human subjects consuming probiotics. The observed changes were increases in levels of antibody-secreting cells and elevated phagocytic activity of monocytes and granulocytes. Taken as a whole, studies in in vitro systems and in a wide range of animal models provide considerable evidence that LAB, and to a lesser extent prebiotics, have the potential to decrease colon cancer risk. The evidence from humans is less persuasive, but nonetheless is suggestive of a cancer-preventing effect of fermented foods.

To consider in greater detail the epidemiology related to colon cancer and diet, the reader is advised to examine a number of reviews quoted within the body of this chapter. These references represent comprehensive insight given by authors including Potter, Slattery and Bingham. 14 Acknowledgement This chapter has been carried out with the financial support from the Commission of the European Communities, specific RTD programme ‘Quality of Life Management of Living Resources’, QLK-2000-00067 ‘Functional foods, gut microflora and healthy ageing’.

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